Fatty Acid Metabolism and Perfusion Mismatch in Acute Chest Pain Syndrome

Acute Aortic Syndrome Presents with Chest Pain

Acute aortic syndrome can be due to acute aortic dissection, intramural hematoma, penetrating atherosclerotic ulcer, or unstable thoracic aneurysm. These life-threatening conditions are clinically indistinguishable, often presenting with acute chest pain. Contrast-enhanced, cardiac-gated multidetector computed tomography (CT) is a highly accurate imaging method for determining the cause of acut...

Fatty acid metabolism: target for metabolic syndrome.

Fatty acids are a major energy source and important constituents of membrane lipids, and they serve as cellular signaling molecules that play an important role in the etiology of the metabolic syndrome. Acetyl-CoA carboxylases 1 and 2 (ACC1 and ACC2) catalyze the synthesis of malonyl-CoA, the substrate for fatty acid synthesis and the regulator of fatty acid oxidation. They are highly regulated...

Chest Pain in Adolescent Japanese Male Mimicking Acute Coronary Syndrome

Acute chest pain with very elevated troponin level and abnormal EKG in adult population is considered sine qua non to acute coronary syndrome (ACS) unless proved otherwise. Similar presentation in adolescent population is seen less often but raises suspicion for ACS. Most common etiology for chest pain with cardiac enzyme elevation in adolescent population is usually viral myopericarditis. The ...

Acute chest pain and paraparesis.

Acute and Chronic Chest Pain

1. To understand the differential diagnosis of chest pain requiring cardiac surgical consultation. 2. To understand the physiology of and rationality for medical treatment of ischemic coronary artery disease. 3. To differentiate acute aortic dissection from myocardial infarction in the emergency setting. 4. To understand initial stabilization of the patient with aortic dissection. 5. To recogni...